Comparing Injecting Drug Users with Others Receiving Outpatient Parenteral Antibiotic Therapy

Comparing Injecting Drug Users with Others Receiving Outpatient Parenteral Antibiotic Therapy

Risk Factors Associated With Outpatient Parenteral Antibiotic Therapy Program Failure Among Intravenous Drug Users

Sixty-one percent of intravenous drug users (IVDUs) who received outpatient parenteral antibiotic therapy (OPAT) failed treatment. Hospital readmission and adverse drug reactions occurred in 25%. By multivariate analysis, time since last IVDU was associated with failure (P = .04). Intravenous drug users requiring OPAT are at high risk for failure; additional studies are needed to explore altern...

Prediction model for 30-day hospital readmissions among patients discharged receiving outpatient parenteral antibiotic therapy.

BACKGROUND Factors associated with readmission for patients prescribed outpatient parenteral antibiotic therapy (OPAT) at hospital discharge have not been definitively identified. The study aim was to develop a model of 30-day readmissions for OPAT patients. METHODS A database comprising 782 OPAT patients treated between 2009 and 2011 at a single academic center was created. Variables collect...

Managing an outpatient parenteral antibiotic therapy team: challenges and solutions

Outpatient parenteral antimicrobial therapy (OPAT) programs should strive to deliver safe, cost effective, and high quality care. One of the keys to developing and sustaining a high quality OPAT program is to understand the common challenges or barriers to OPAT delivery. We review the most common challenges to starting and managing an OPAT program and give practical advice on addressing these i...

Ceftriaxone-related agranulocytosis during outpatient parenteral antibiotic therapy.

4 Song W, Moland ES, Hanson ND et al. Failure of cefepime therapy in treatment of Klebsiella pneumoniae bacteremia. J Clin Microbiol 2005; 43: 4891–4. 5 Kim YK, Pai H, Lee HJ et al. Bloodstream infections by extended-spectrum b-lactamase-producing Escherichia coli and Klebsiella pneumoniae in children: epidemiology and clinical outcome. Antimicrob Agents Chemother 2002; 46: 1481–91. 6 Farmer JJ...